Metal-coordinated nitrogen-doped C₆₀ is attractive for use in hydrogen fuel cells for oxygen reduction at the cathode. The detailed reaction pathways for oxygen reduction reaction (ORR) on MnN4 embedded C₆₀ (MnN4-C₆₀) is investigated using the dispersion-corrected density functional theory (DFT-D) method. It is found that the MnN4 is the active center for all the possible elementary steps of the ORR. The four-electron OOH dissociation pathway and the O₂ direct dissociation path are both the probable paths for ORR on the MnN4-C₆₀. The MnN4-C₆₀ could promote ORR via four kinds of reaction paths and therefore has the novel catalytic activity for ORR comparable to (or even higher than) that of Pt catalysts.